Important information for patients attending Gynaecology services
What is HPV?
Human Papillomavirus (HPV) is a very common virus
Most people will have HPV at some point in their lives
In most cases, the immune system clears HPV naturally
However, sometimes the virus stays in the body and can cause:
- Abnormal cervical cells
- Cervical cancer
- Vaginal and vulval cancers
How does smoking affect HPV?
Smoking makes it harder for your body to clear HPV. Cigarette smoke contains thousands of harmful chemicals and nicotine. These chemicals:
- Weaken the immune system
- Reduce the body’s ability to fight infection
- Damage cervical cells directly
- Increase inflammation
This means:
- HPV is more likely to persist
- Cell changes are more likely to develop
- The risk of cervical cancer increases
- Treatment for abnormal cells may be less effective
Research shows that people who smoke are significantly more likely to develop high-grade cervical cell changes compared to non-smokers.
Stopping smoking improves your body’s ability to fight HPV.
Why stopping smoking matters, especially now
If you:
- Have tested positive for HPV
- Have abnormal smear results
- Are under colposcopy follow-up
- Have had treatment for cervical cell changes
Stopping smoking is one of the most important things you can do to reduce your future cancer risk.
Quitting can:
- Improve immune response
- Reduce the likelihood of persistent HPV
- Lower the risk of recurrence after treatment
- Improve healing
Even stopping for a short period makes a difference.
“But I’m stressed, how will I cope?”
Nicotine is addictive, but it is not what causes cancer.
The harm comes from tobacco smoke.
We can provide:
- Nicotine replacement therapy (patches + fast-acting support)
- Specialist behavioural support
- Follow-up calls
- Advice tailored to you
You do not have to quit alone.
How to get support at UHNM
If you would like help to stop smoking:
- Speak to your gynaecology nurse or doctor
- Ask for a referral to the Tobacco Dependency Team
- Contact the on-site clinic
- Community support is also available after discharge
Support is available for patients, staff and visitors.
The Evidence: Smoking, HPV and Cervical Cancer
National guidance and research clearly show that smoking increases the risk of cervical cancer and persistent HPV infection.
The NHS Cervical Screening Programme identifies smoking as a significant risk factor for cervical cancer.
- Research shows that people who smoke are around twice as likely to develop cervical cancer compared to non-smokers.
- Smoking weakens the immune system, making it harder for the body to clear HPV naturally.
- Harmful chemicals from tobacco smoke have been found in cervical mucus, meaning smoking directly affects cervical cells.
- Stopping smoking improves immune function and reduces the risk of ongoing cell changes.
The National Institute for Health and Care Excellence (NICE) recommends that all healthcare professionals use opportunities such as screening results, abnormal findings, and follow-up appointments to support people to stop smoking.
Stopping smoking is one of the most effective actions you can take to reduce your risk of cervical cancer.
Why this matters if you are HPV positive
If you have tested positive for HPV or have abnormal cervical cells:
- Quitting smoking increases your chance of clearing HPV.
- It reduces the likelihood of further cell changes.
- It may reduce the risk of recurrence after treatment.
- It supports better healing following colposcopy or procedures.
Even stopping now, after a positive result, can make a difference.