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About This Test

Department: Biochemistry


  • Gel/clotted (yellow/red top)



Turnaround Time:

1 week


Macroprolactin is a complex of prolactin with another protein, most commonly IgG. Some patients have high levels of naturally occurring macroprolactin, which has minimal biological activity in vivo, but may cross react with the local prolactin assay, leading to falsely elevated results.

Consider investigation for macroprolactin if prolactin is consistently elevated without apparent underlying cause. Macroprolactin analysis will be added on to any sample with unexplained elevated prolactin at the discretion of the Duty Biochemist.

Other Comments:

An interpretive comment will be attached to all macroprolactin analyses.